I've tried 3 but that doesn't include Anyrail unfortunately. There was an Atlas one which isn't available anymore. I tried it but wasn't fond of it though I can't remember why.
Templot is a powerful bit of software particularly for planning handlaid prototypical track but I didn't persevere with it long enough to appreciate its strengths. Although it was a bit over my head I'd like to give it another crack one day.
Scarm came along and I've found it suits my needs. Although one can render buildings, landscapes and other objects, I find that a bit of a chore. I see on the Anyrail site screenshots of populated sculpted landscapes too and although it appears to have predefined scenery items including signals in its library, it's the trackplan itself I'm interested in and the rest I can visualise or add with a pencil when it's printed. I just needed a way of putting together proprietary track including gradients and Scarm does that really well for me. I'd guess Anyrail would be as easy as Scarm to learn and it might be worth trying both but since I came across and liked Scarm first, like John says, I'm unlikely to change.